USE OF MOK MODULATING AGENTS FOR THE TREATMENT OF INFLAMMATORY DISEASES AND NEURODEGENERATIVE DISEASES
| Application number: |  PCT/ES2018/070216 (21.03.2018)
| | Applicant: | FUNDACIÓN PÚBLICA ANDALUZA PROGRESO Y SALUD (ES)
Avda. Americo Vespucio 15, Edificio S-2 41092 Sevilla 41092, ESPAÑA | | Inventor/s: | ROODVELDT CATELLANI, Cintia (ES);
LEAL LASARTE, María Magdalena (ES);
MUÑOZ FRANCO, Jaime (ES);
POZO PÉREZ, David (ES);
| | Abstract: | The invention relates to compounds and compositions that can modulate the activity of MOK (MAPK/MAK/MRK) or any of the biologically active variants and isoforms thereof, and to a method for selecting same for the treatment of diseases with an inflammatory component and/or conformational neurodegenerative diseases and, more specifically, for the treatment of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD).
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