METHOD OF OBTAINING HYDROGELS OF CYCLODEXTRINS WITH GLYCIDYL ETHERS, COMPOSITIONS THUS OBTAINED AND APPLICATIONS THEREOF
Application number: | PCT/ES2006/000096 (15.02.2006) E06725794 (15.02.2006)
| Priority number: | ES20050000556 (25.02.2005)
| Applicant: | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) CITT - EDIFICIO CACTUS, CAMPUS SUR, 15782 SANTIAGO DE COMPOSTELA | Inventor/s: | ALVAREZ LORENZO, Carmen (ES); RODRÍGUEZ-TENREIRO SÁNCHEZ, Carmen (ES); TORRES LABANDEIRA, Juan José (ES); CONCHEIRO NINE, Angel (ES);
| Abstract: | The invention relates to a method of obtaining hydrogels based on (i) cyclodextrins, (ii) cyclodextrins and cellulose ethers or (iii) cyclodextrins and guar gum or the derivatives of same, using molecules containing two or more glycidyl ether groups in the structure thereof as a cross-linking agent. The invention also relates to the compositions thus obtained, which can include active substances and pharmaceuticals and which form inclusion complexes with cyclodextrins. The invention further relates to the use of same as components of controlled-release devices, such as transdermal pharmaceutical forms, vaginal, otic, ocular, rectal, oral or buccal transmucosal forms and parenteral implants, which are designed to administer active substances or pharmaceuticals to humans, animals or plants, or as components of cosmetic formulations. In addition, the invention relates to the use of said compositions as chelating agents in the extraction of biological or toxic molecules from living organisms or contaminating substances from water.
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